mouse anti human p selectin (R&D Systems)
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mouse anti human p selectin
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Mouse Anti Human P Selectin, supplied by R&D Systems, used in various techniques. Bioz Stars score: 94/100, based on 5 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/anti+human+p+selectin/Human+E-Selectin%2FP-Selectin+(CD62E%2FP)+APC-conjugated+Antibody/pmc13021478-120-97-100
Average 94 stars, based on 5 article reviews
Mouse Anti Human P Selectin, supplied by R&D Systems, used in various techniques. Bioz Stars score: 94/100, based on 5 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/anti+human+p+selectin/Human+E-Selectin%2FP-Selectin+(CD62E%2FP)+APC-conjugated+Antibody/pmc13021478-120-97-100
Average 94 stars, based on 5 article reviews
mouse anti human p selectin - by Bioz Stars,
2026-10
94/100 stars
Images
1) Product Images from "Molecular determinants of STEC-HUS: from complement activation to microvascular thrombosis"
Article Title: Molecular determinants of STEC-HUS: from complement activation to microvascular thrombosis
Journal: Frontiers in Immunology
doi: 10.3389/fimmu.2026.1749811
Figure Legend Snippet: Prothrombotic effects of STEC-HUS serum are dependent on WPB exocytosis from endothelial cells. P-selectin (A) and vWF (B) expression on unstimulated HMEC-1 exposed to serum from patients with acute STEC-HUS (n = 5 for P-selectin experiments; n = 6 for vWF experiments), in the presence or in the absence of different complement inhibitors (sCR1, 150 µg/mL; factor B inhibitor, iptacopan,10 µM; eculizumab 100 µg/mL) or to a pool of control sera (normal human serum, NHS), run in parallel. Results are shown as pixel 2 /high-power field (HPF) of stained surface area. Data are mean ± SD. Circles represent single patients’ data. The addition of either sCR1, or iptacopan or eculizumab to patient’s serum significantly decrease both P-selectin and vWF expression induced by patient’s serum alone. *P < 0.05 vs STEC-HUS serum alone (ANOVA, followed by Tukey’s multiple comparisons test for data of P-selectin expression and by Holm-Šídák’s multiple comparisons test for data of vWF expression). (C) Endothelial surface area covered by thrombi on ADP-activated HMEC-1 exposed to serum from STEC-HUS patients collected during the acute phase of the disease and then perfused with whole blood. Before the experiments, HMEC-1 were left for 16 hours with medium added or not with the RalA inhibitor BQU57 (10 µM). Data are expressed as mean ± SD of percentages of serum-induced thrombus formation in respect to a pool of control sera (normal human serum, NHS), run in parallel in each experiment and set as 100% (n = 3 independent experiments). Circles indicate single patients’ data. Horizontal dashed lines indicate upper and lower limits of the normal range . *P < 0.05 (paired Student’s t test). (D) Representative confocal microscopy images (original magnification X200) of experiments of thrombus formation (green staining) relative to
Techniques Used: Expressing, Control, Staining, Confocal Microscopy
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